News

We are pleased to announce that the results of our collaborative research with Kobe University were presented at the 4th International Process Intensification Conference (IPIC4), held in Canada from June 21 to 25, 2026.

IPIC4 is an international conference dedicated to innovative technologies and research that improve process efficiency and sustainability across the chemical, pharmaceutical, food, and energy industries.

Kobe University presented the following two research papers:

・Information-Driven Process Intensification for Polymorph Control in Continuous Crystallization

・Hydrodynamics and Mass Transfer of Liquid-Liquid Slug Flow in a Narrow-Gap Taylor-Couette Flow Reactor for Process Intensification

Our collaborative research utilized TVF, the Taylor-Couette Flow Continuous Crystallization & Reaction System, to investigate the effects of reactor gap width and residence time on polymorph control during continuous crystallization.

The study also explored liquid-liquid slug flow, a unique flow regime that suppresses axial mixing within the Taylor-Couette flow field and significantly narrows the residence time distribution. Research is underway to identify the operating conditions required to generate this flow pattern, which is expected to enhance reaction control and process efficiency.

These findings are expected to contribute to the development of more efficient crystallization and reaction processes for pharmaceutical and chemical manufacturing.

Tipton will continue its collaborative research with Kobe University to further advance TVF technology and expand the application of Taylor-Couette Flow in continuous processing.

Click here for the TVF information page >

Click here to watch a movie of TVF＞

Kobe University Omura Laboratory – Click here＞

On June 11, 2026, we hosted the 7th Joint Research Results Presentation Meeting at our headquarters hall, bringing together researchers from Kanazawa University, Kobe University, Kumamoto University, and Tipton.

This year, four research topics were presented:

• Kanazawa University: Research on elucidating the processing mechanisms of gyro-type mass finishing and modeling edge-rounding formation in pressure-assisted mass finishing processes.
• Kobe University: Proposal of new business models utilizing TVF® and presentation of related research outcomes.
• Kumamoto University: Manufacturing methods for lipid nanoparticles (LNPs) using TVF® and evaluation of their effectiveness.
• Tipton: Development progress and application testing of the new “ECX Ps” system for granulation and coating of fine particles.

The meeting showcased a wide range of research achievements, including advancements in mass finishing technology, new applications of TVF®, and new product development. Active discussions were held across multiple disciplines, fostering collaboration and innovation among academia and industry.

These research outcomes will be progressively published through academic conferences and scientific journals. We remain committed to promoting open innovation through industry-academia collaboration and advancing the development of next-generation technologies.

Kanazawa University Hashimoto Laboratory – Click here＞
Kobe University Omura Laboratory – Click here＞
Kumamoto University Motoyama Laboratory – Click here＞

The TVF Taylor Couette Flow Continuous Crystallization & Reaction System delivers outstanding temperature control performance, achieving stable temperature control within ±0.2°C during continuous operation.

In crystallization processes, even slight temperature fluctuations can significantly affect particle size distribution and crystal quality. Therefore, maintaining stable outlet liquid temperature control within approximately ±0.5°C is essential for achieving consistent process performance.

To minimize heat generation caused by the drive system rotating shaft drive mechanism, sealing components, and shear forces inside the reactor, TVF incorporates several advanced temperature-control technologies:

・High-precision rotating shaft accuracy within ±5 μm to reduce heat generation in the drive system its drive mechanism

・Proprietary double mechanical seal design that minimizes heat generation

・High-efficiency outer jacket structure for superior heat transfer performance

By combining these advanced technologies, TVF® significantly improves temperature stability during continuous operation. Testing confirmed that fluctuations in outlet liquid temperature were reduced from approximately ±2°C in conventional systems to a stable range of ±0.2°C.

This high level of temperature control performance capability has led to the adoption of TVF in continuous crystallization and continuous flow synthesis applications.

Click here for the TVF information page >

Click here to watch a movie of TVF＞

Click here for TVF product catalog＞

Exhibition Details

Event: FOOMA JAPAN 2026

Dates: June 2 (Tue) – June 5 (Fri), 2026

Venue: Tokyo Big Sight, Japan

Booth No.: East Hall 3, E3-21-15

For more information: FOOMA JAPAN

Featured Products

■ ECX – Coating System

A high-performance coating system designed to achieve shorter processing time, reduced material loss, and labor savings.

Its proprietary multi-spin structure generates a vortex flow, enabling fast and uniform coating.

ECX is widely used by leading confectionery manufacturers for applications such as chocolate, coated nuts, and gummies.

In addition to coating, it also performs functions such as granulation, spheronization, and mixing.

■ Machine & Floor Liquid (Cleaner)

A versatile cleaning solution for food processing environments, suitable for machinery and floor cleaning.

Effectively removes oil and grease while containing antibacterial agents to help reduce the risk of foodborne contamination.

Live cleaning demonstrations will be conducted at the exhibition.

By leveraging innovative processing and cleaning technologies, we support food manufacturers in improving productivity, efficiency, and sanitation standards.

We look forward to welcoming you at our booth.

Click here to watch a movie of ECX＞

Click here for ECX product catalog＞

We are pleased to announce that we will exhibit our “TVF” Taylor Couette flow nano reactor and “ECX” multi-spin processing system at the 28th Interphex Japan, a leading exhibition for pharmaceutical and biotechnology manufacturing.

Exhibition Details

• Event: The 28th Interphex Japan

• Dates: May 20 (Wed) – May 22 (Fri), 2026

• Venue: Makuhari Messe , Japan

• Booth No.: Hall 6, Booths 31-39

Featured Technologies

■ TVF – Taylor Couette Flow Nano Reactor
An innovative continuous reaction and crystallization system designed for the pharmaceutical, food, cosmetics, and chemical industries.
TVF enables the transformation of API manufacturing through continuous flow synthesis and continuous crystallization, improving efficiency and process control.

■ ECX – Multi-Spin Granulation & Coating System
A next-generation processing system for the pharmaceutical and food industries, capable of granulation, coating, spheronization, and mixing.
It can handle a wide range of materials, from fine particles to tablet-scale products.

At the exhibition, we will conduct live demonstrations of both systems.
By leveraging advanced fluid technology, our solutions address key challenges in modern pharmaceutical manufacturing, including shorter development timelines and improved productivity in the VUCA era.

Our experienced team will be on hand to propose practical solutions tailored to your needs.

We look forward to welcoming you at our booth.

Click here to watch a movie of TVF＞

Click here for TVF product catalog＞

Click here to watch a movie of ECX＞

Click here for ECX product catalog＞